Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
Swit_0946Transcriptional regulator, TetR family; PFAM: regulatory protein, TetR. (206 aa)    
Predicted Functional Partners:
Swit_0943
PFAM: glycine cleavage T protein (aminomethyl transferase); FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Glycine cleavage T-protein, C-terminal barrel; Belongs to the GcvT family.
  
  
 0.608
Swit_0942
PFAM: Sarcosine oxidase, gamma subunit.
       0.586
Swit_0944
PFAM: Sarcosine oxidase, delta subunit, heterotetrameric.
       0.586
Swit_0945
TIGRFAM: sarcosine oxidase, beta subunit family; PFAM: FAD dependent oxidoreductase.
     
 0.586
folD1
Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
   
 
 0.524
Swit_0947
PFAM: class II aldolase/adducin family protein.
       0.519
Swit_3884
PFAM: dehydrogenase, E1 component; Transketolase, central region; Transketolase domain protein.
  
     0.461
purU
Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).
       0.455
Swit_3366
PFAM: regulatory protein, TetR.
  
     0.426
Swit_0938
PFAM: peptidase S15; X-Pro dipeptidyl-peptidase C-terminal domain protein.
 
     0.415
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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