Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene co-occurrence
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[Homology]
Score
Swit_1099Signal transduction histidine kinase; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, dimerisation/phosphoacceptor. (335 aa)    
Predicted Functional Partners:
Swit_3925
PFAM: response regulator receiver.
 
   
 0.790
Swit_3926
PFAM: histidine kinase, HAMP region domain protein; histidine kinase, dimerisation/phosphoacceptor.
  
     0.766
Swit_4627
PFAM: response regulator receiver.
 
   
 0.740
Swit_0073
Response regulator receiver protein.
 
   
 0.640
Swit_1160
Multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; CHASE3 domain protein; PAS fold domain protein; SMART: PAS domain containing protein.
 
   
 0.545
Swit_1098
Hypothetical protein.
       0.496
Swit_2540
PFAM: response regulator receiver.
     
 0.483
Swit_3435
PFAM: response regulator receiver.
 
   
 0.482
Swit_3924
RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2; Belongs to the sigma-70 factor family. ECF subfamily.
 
   
 0.466
Swit_1100
Hypothetical protein.
       0.403
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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