STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Swit_1108PFAM: Activator of Hsp90 ATPase 1 family protein. (149 aa)    
Predicted Functional Partners:
Swit_4586
PFAM: 3-demethylubiquinone-9 3-methyltransferase.
    0.854
Swit_1189
PFAM: Activator of Hsp90 ATPase 1 family protein.
  
     0.770
Swit_0625
Transcriptional regulator, ArsR family; PFAM: regulatory protein, ArsR; Helix-turn-helix, type 11 domain protein.
 
  
 0.738
Swit_1190
Transcriptional regulator, ArsR family; PFAM: regulatory protein, ArsR.
 
  
 0.727
Swit_2245
PFAM: Glutathione S-transferase, N-terminal domain; Belongs to the GST superfamily.
 
   
 0.625
Swit_0145
PFAM: Glutathione S-transferase, N-terminal domain.
 
   
 0.606
Swit_2159
PFAM: protein of unknown function DUF1428.
 
     0.593
Swit_1109
Putative RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; Sigma-70, region 4 type 2; Belongs to the sigma-70 factor family.
       0.578
Swit_1110
PFAM: DGPFAETKE family protein.
       0.578
ku
Ku family containing protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family.
  
   
 0.577
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.