Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Swit_1108PFAM: Activator of Hsp90 ATPase 1 family protein. (149 aa)    
Predicted Functional Partners:
Swit_4586
PFAM: 3-demethylubiquinone-9 3-methyltransferase.
    0.838
Swit_1189
PFAM: Activator of Hsp90 ATPase 1 family protein.
  
     0.770
Swit_0625
Transcriptional regulator, ArsR family; PFAM: regulatory protein, ArsR; Helix-turn-helix, type 11 domain protein.
 
  
 0.746
Swit_1190
Transcriptional regulator, ArsR family; PFAM: regulatory protein, ArsR.
 
  
 0.732
Swit_1109
Putative RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; Sigma-70, region 4 type 2; Belongs to the sigma-70 factor family.
       0.580
Swit_1110
PFAM: DGPFAETKE family protein.
       0.580
Swit_2159
PFAM: protein of unknown function DUF1428.
 
     0.546
Swit_4587
PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase.
       0.475
Swit_0041
PFAM: Domain of unknown function DUF1801.
 
     0.447
Swit_0489
PFAM: bifunctional deaminase-reductase domain protein.
 
     0.425
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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