Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Swit_1121Conserved hypothetical protein. (268 aa)    
Predicted Functional Partners:
Swit_1120
Nucleotidyltransferase/DNA polymerase involved in DNA repair-like protein.
 
  
 0.992
dnaE2
DNA polymerase III, alpha subunit; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.
 
  
 0.943
dinB
DNA-directed DNA polymerase; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
  
  
 0.849
Swit_1122
Hypothetical protein.
       0.605
Swit_3881
PFAM: protein of unknown function DUF983.
  
     0.582
Swit_2327
Uncharacterized protein.
  
     0.569
Swit_2765
PFAM: protein of unknown function DUF983.
  
     0.562
Swit_2823
PFAM: protein of unknown function DUF1052.
  
     0.534
Swit_1930
Conserved hypothetical protein.
  
     0.510
Swit_1123
Transcriptional regulator, MerR family; PFAM: regulatory protein, MerR; Transcription regulator MerR, DNA binding.
       0.499
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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