STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Swit_1147Molecular chaperone (small heat shock protein)-like protein; Belongs to the small heat shock protein (HSP20) family. (196 aa)    
Predicted Functional Partners:
lon-2
ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
 
  
 0.945
Swit_0619
PFAM: heat shock protein Hsp20; Belongs to the small heat shock protein (HSP20) family.
  
  
 0.831
Swit_0126
TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase, central domain protein; Clp N terminal domain protein; ATPase associated with various cellular activities, AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; Belongs to the ClpA/ClpB family.
  
 
 0.732
clpB
ATPase AAA-2 domain protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.
  
 
 0.732
Swit_1148
PFAM: Carboxylesterase, type B; Belongs to the type-B carboxylesterase/lipase family.
  
 
 0.622
Swit_4023
TIGRFAM: cell shape determining protein, MreB/Mrl family; PFAM: cell division protein FtsA; cell shape determining protein MreB/Mrl.
   
 
 0.604
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 
 0.556
Swit_4523
PFAM: glycosyl transferase, family 2.
  
  
 0.535
Swit_4526
PFAM: glycosyl transferase, family 2.
     
 0.516
Swit_0771
Molecular chaperone-like protein.
  
 
 0.511
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.