STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Swit_1235PFAM: CHASE2 domain protein; Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein. (671 aa)    
Predicted Functional Partners:
Swit_1477
Putative adenylate/guanylate cyclase; TIGRFAM: PAS sensor protein; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; GAF domain protein; histidine kinase, HAMP region domain protein; PAS fold-4 domain protein; PAS fold domain protein.
 
 0.990
Swit_0231
Putative adenylate/guanylate cyclase; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; CHASE2 domain protein.
  
 0.964
Swit_1237
PFAM: Sulfate transporter/antisigma-factor antagonist STAS.
 
 
 0.955
Swit_1493
Putative anti-sigma regulatory factor, serine/threonine protein kinase.
 
 
 0.944
Swit_1492
Anti-sigma-factor antagonist; TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; Belongs to the anti-sigma-factor antagonist family.
 
 
 0.932
Swit_1232
Putative anti-sigma regulatory factor, serine/threonine protein kinase; PFAM: ATP-binding region, ATPase domain protein domain protein.
 
 
 0.927
cpdA
Metallophosphoesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.
     
 0.905
Swit_0253
TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase.
    
  0.904
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
    
  0.903
Swit_3121
TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase, barrel; Pyruvate kinase, alpha/beta; Belongs to the pyruvate kinase family.
    
  0.903
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.