Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-expression
Experiments
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[Homology]
Score
Swit_1405PFAM: 20S proteasome, A and B subunits. (260 aa)    
Predicted Functional Partners:
Swit_0520
PFAM: protein of unknown function DUF403.
 
    0.909
Swit_0521
PFAM: transglutaminase domain protein; transglutaminase, N-terminal domain protein.
 
    0.892
Swit_0519
PFAM: protein of unknown function DUF404; protein of unknown function DUF407.
 
    0.869
Swit_4759
PFAM: protein of unknown function DUF403; protein of unknown function DUF404; protein of unknown function DUF407.
 
    0.824
Swit_4075
PFAM: transglutaminase domain protein; transglutaminase, N-terminal domain protein.
 
    0.770
Swit_4391
PFAM: transglutaminase domain protein.
 
    0.744
Swit_4760
PFAM: transglutaminase domain protein; transglutaminase, N-terminal domain protein.
 
    0.644
queE
Organic radical activating enzymes-like protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
       0.548
queC
exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.
       0.548
Swit_4758
PFAM: transglutaminase domain protein; transglutaminase, N-terminal domain protein.
 
    0.495
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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