Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Swit_1447PFAM: Alpha/beta hydrolase fold-3 domain protein. (308 aa)    
Predicted Functional Partners:
Swit_1448
PFAM: AMP-dependent synthetase and ligase.
  
 0.846
Swit_1439
Dipeptidyl aminopeptidase/acylaminoacyl-peptidase-like protein.
 
   
 0.667
Swit_1446
PFAM: regulatory protein, LuxR.
       0.516
Swit_0892
Flavoprotein involved in K+ transport-like protein.
  
 0.450
Swit_2991
NADH-quinone oxidoreductase, chain G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family.
   
 
 0.428
Swit_4132
PFAM: FAD dependent oxidoreductase.
  
 0.420
Swit_2012
PFAM: FAD dependent oxidoreductase.
  
 0.412
Swit_2821
PFAM: Ankyrin.
   
 0.400
Swit_3098
PFAM: Ankyrin.
   
 0.400
Swit_3235
PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
  
 
 0.400
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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