Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Swit_1476Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; Belongs to the LysR transcriptional regulatory family. (300 aa)    
Predicted Functional Partners:
Swit_1473
TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: ferredoxin; 4Fe-4S ferredoxin, iron-sulfur binding domain protein; molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region.
 
   
 0.828
Swit_1474
PFAM: Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit.
 
   
 0.756
Swit_0173
Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; Belongs to the LysR transcriptional regulatory family.
  
     0.753
Swit_1475
PFAM: NADH dehydrogenase (ubiquinone), 24 kDa subunit.
 
   
 0.751
Swit_3518
Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; Belongs to the LysR transcriptional regulatory family.
  
     0.741
fdhD
Formate dehydrogenase family accessory protein FdhD; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family.
 
     0.740
Swit_1472
Formate dehydrogenase delta subunit.
 
   
 0.738
Swit_0474
Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; Belongs to the LysR transcriptional regulatory family.
  
     0.733
Swit_0960
Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; Belongs to the LysR transcriptional regulatory family.
  
     0.721
Swit_1777
Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; Belongs to the LysR transcriptional regulatory family.
  
     0.718
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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