Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Swit_1487PFAM: histidine kinase, HAMP region domain protein; Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein. (535 aa)    
Predicted Functional Partners:
Swit_1493
Putative anti-sigma regulatory factor, serine/threonine protein kinase.
 
 
 0.937
Swit_1492
Anti-sigma-factor antagonist; TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; Belongs to the anti-sigma-factor antagonist family.
 
 
 0.934
Swit_1232
Putative anti-sigma regulatory factor, serine/threonine protein kinase; PFAM: ATP-binding region, ATPase domain protein domain protein.
 
 
 0.905
Swit_1237
PFAM: Sulfate transporter/antisigma-factor antagonist STAS.
 
 
 0.887
Swit_1263
Rod binding-like protein.
   
    0.762
Swit_2540
PFAM: response regulator receiver.
  
  
 0.756
Swit_0717
FO synthase subunit 1 / FO synthase subunit 2; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB.
   
  
 0.744
Swit_1489
PFAM: histidine kinase, HAMP region domain protein.
 
  
0.723
Swit_1488
ATP/ADP translocase-like protein.
 
   
 0.719
Swit_3806
PFAM: Sulfate transporter/antisigma-factor antagonist STAS.
  
 
 0.715
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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