Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Swit_1489PFAM: histidine kinase, HAMP region domain protein. (375 aa)    
Predicted Functional Partners:
Swit_1488
ATP/ADP translocase-like protein.
 
     0.968
Swit_1160
Multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; CHASE3 domain protein; PAS fold domain protein; SMART: PAS domain containing protein.
  
 
 0.816
Swit_2540
PFAM: response regulator receiver.
  
 
 0.810
Swit_1490
Putative transcriptional regulator, Crp/Fnr family.
       0.786
Swit_1491
Hypothetical protein.
       0.781
Swit_1477
Putative adenylate/guanylate cyclase; TIGRFAM: PAS sensor protein; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; GAF domain protein; histidine kinase, HAMP region domain protein; PAS fold-4 domain protein; PAS fold domain protein.
  
 
 0.751
Swit_1487
PFAM: histidine kinase, HAMP region domain protein; Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein.
 
  
0.723
Swit_1493
Putative anti-sigma regulatory factor, serine/threonine protein kinase.
 
 
 0.693
Swit_1232
Putative anti-sigma regulatory factor, serine/threonine protein kinase; PFAM: ATP-binding region, ATPase domain protein domain protein.
 
 
 0.692
Swit_4432
PAS/PAC sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein.
  
 
 0.684
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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