Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Swit_1528PFAM: alpha/beta hydrolase fold. (278 aa)    
Predicted Functional Partners:
Swit_0888
PFAM: alpha/beta hydrolase fold.
  
   
 0.760
Swit_1445
PFAM: alpha/beta hydrolase fold.
  
     0.757
Swit_1653
PFAM: alpha/beta hydrolase fold.
  
   
 0.672
Swit_1530
PFAM: AMP-dependent synthetase and ligase.
  
 
 0.655
Swit_1529
PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
     
 0.601
Swit_1531
Rieske (2Fe-2S) domain protein; PFAM: ring hydroxylating dioxygenase, alpha subunit; Rieske [2Fe-2S] domain protein.
   
 
 0.589
Swit_1526
PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein; Belongs to the TPP enzyme family.
    
 0.584
Swit_1532
PFAM: aromatic-ring-hydroxylating dioxygenase, beta subunit.
  
  
 0.563
Swit_3309
PFAM: alpha/beta hydrolase fold.
  
   
 0.547
Swit_3311
PFAM: alpha/beta hydrolase fold.
  
   
 0.523
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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