Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Swit_1547PFAM: fumarylacetoacetate (FAA) hydrolase. (329 aa)    
Predicted Functional Partners:
Swit_1548
ABC-type nitrate/sulfonate/bicarbonate transport systems periplasmic components-like protein.
  
  
 0.794
Swit_4308
5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase; PFAM: fumarylacetoacetate (FAA) hydrolase.
  
     0.763
Swit_1549
Vanillate monooxygenase; PFAM: Rieske [2Fe-2S] domain protein.
     
 0.690
argF
Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
     
 0.588
hppA
V-type H(+)-translocating pyrophosphatase; Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.
     
 0.584
Swit_1546
PFAM: alpha/beta hydrolase fold.
  
  
 0.487
Swit_1545
PFAM: aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 
 0.483
Swit_1550
PFAM: Rieske [2Fe-2S] domain protein.
     
 0.459
Swit_1557
PFAM: homogentisate 1,2-dioxygenase.
  
  
 0.403
hmgA
Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.
  
  
 0.403
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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