Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Swit_1571PFAM: NADH:flavin oxidoreductase/NADH oxidase. (455 aa)    
Predicted Functional Partners:
Swit_1570
PFAM: short-chain dehydrogenase/reductase SDR; KR.
  
  
 0.782
Swit_1569
PFAM: monooxygenase, FAD-binding; FAD dependent oxidoreductase.
     
 0.778
Swit_1568
TIGRFAM: succinic semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
  
 0.489
Swit_3196
PFAM: Electron transfer flavoprotein, alpha/beta-subunit-like.
  
 
 0.410
Swit_1567
PFAM: dihydrodipicolinate synthetase; Belongs to the DapA family.
     
 0.401
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
Server load: low (8%) [HD]