Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Swit_1693Mandelate racemase/muconate lactonizing enzyme, N-terminal domain protein; Catalyzes the dehydration of D-mannonate. Has no detectable activity with a panel of 70 other acid sugars (in vitro). (402 aa)    
Predicted Functional Partners:
Swit_1886
PFAM: Mannitol dehydrogenase, C-terminal domain; Mannitol dehydrogenase rossman, N-terminal domain.
 
  
 0.983
Swit_1889
PFAM: Mandelate racemase/muconate lactonizing enzyme, N-terminal domain protein; Mandelate racemase/muconate lactonizing enzyme, C-terminal domain protein.
  
  
 
0.900
Swit_1890
2-keto-3-deoxygluconate kinase; PFAM: PfkB domain protein.
 
  
 0.879
Swit_1699
PFAM: PfkB domain protein.
 
  
 0.856
uxaC
PFAM: Glucuronate isomerase.
 
   
 0.855
Swit_1130
TIGRFAM: sugar-phosphate isomerase, RpiB/LacA/LacB family; ribose 5-phosphate isomerase B; PFAM: Ribose/galactose isomerase.
     
  0.800
Swit_1941
PFAM: ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family.
     
  0.800
Swit_1692
Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; Belongs to the LysR transcriptional regulatory family.
     
 0.544
Swit_2699
2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
  
    0.453
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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