STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Swit_1729PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase. (136 aa)    
Predicted Functional Partners:
Swit_1728
PFAM: major facilitator superfamily MFS_1.
  
  
 0.646
Swit_2975
Citryl-CoA lyase; PFAM: HpcH/HpaI aldolase; Belongs to the HpcH/HpaI aldolase family.
  
  
 0.536
Swit_3238
PFAM: HpcH/HpaI aldolase; Belongs to the HpcH/HpaI aldolase family.
  
  
 0.536
Swit_1730
PFAM: AMP-dependent synthetase and ligase.
  
  
 0.532
Swit_2757
Hypothetical protein.
 
  
 0.500
Swit_1312
TIGRFAM: Succinate dehydrogenase, cytochrome b556 subunit; PFAM: succinate dehydrogenase, cytochrome b subunit.
 
  
 0.465
edd-2
6-phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family.
  
    0.457
Swit_0939
PFAM: FAD dependent oxidoreductase; glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein, C-terminal barrel; Belongs to the GcvT family.
 
   
 0.439
Swit_3235
PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
  
  
 0.409
nuoI
NADH-quinone oxidoreductase, chain I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
  
  
 0.407
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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