Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Swit_1744PFAM: alpha/beta hydrolase fold. (318 aa)    
Predicted Functional Partners:
Swit_1743
PFAM: cytochrome P450.
 
 0.738
Swit_1741
PFAM: Epoxide hydrolase domain protein.
 
     0.724
Swit_1746
PFAM: Enoyl-CoA hydratase/isomerase.
  
 0.686
Swit_1742
Hypothetical protein.
 
     0.678
Swit_1740
PFAM: alpha/beta hydrolase fold.
 
   
 0.645
Swit_1653
PFAM: alpha/beta hydrolase fold.
  
   
 0.583
Swit_3274
PFAM: acyl-CoA dehydrogenase domain protein.
 
 0.570
Swit_1603
PFAM: acyl-CoA dehydrogenase domain protein.
 
 0.560
Swit_1739
PFAM: glucose-methanol-choline oxidoreductase; FAD dependent oxidoreductase; GMC oxidoreductase.
     
 0.557
Swit_3398
PFAM: acyl-CoA dehydrogenase domain protein.
 
 0.555
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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