Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Swit_1753PFAM: amidohydrolase 2. (333 aa)    
Predicted Functional Partners:
nbaC
3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.
 
  
  0.973
Swit_3519
PFAM: aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
 
 
 0.936
Swit_1749
PFAM: amidohydrolase 2.
 
     0.822
Swit_1756
PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase.
 
   
 0.807
Swit_1754
PFAM: alpha/beta hydrolase fold.
     
 0.782
Swit_1617
PFAM: amidohydrolase 2.
  
     0.768
Swit_1755
PFAM: short-chain dehydrogenase/reductase SDR.
  
    0.768
Swit_1757
PFAM: aromatic-ring-hydroxylating dioxygenase, beta subunit.
 
   
 0.736
Swit_3645
PFAM: amidohydrolase 2.
  
     0.715
Swit_1758
PFAM: ring hydroxylating dioxygenase, alpha subunit; Rieske [2Fe-2S] domain protein.
     
 0.702
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
Server load: low (12%) [HD]