Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
Swit_1785PFAM: amidohydrolase; Amidohydrolase 3. (459 aa)    
Predicted Functional Partners:
Swit_1786
Hypothetical protein.
       0.750
Swit_1784
Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; Belongs to the LysR transcriptional regulatory family.
     
 0.716
Swit_1787
PFAM: Endoribonuclease L-PSP.
 
  
 0.638
Swit_1782
PFAM: intradiol ring-cleavage dioxygenase; Catechol dioxygenase, N-terminal domain protein.
 
     0.580
Swit_1780
PFAM: protein of unknown function DUF849.
 
     0.549
Swit_1788
PFAM: amidohydrolase 2.
     
 0.493
Swit_1778
PFAM: Cupin 2, conserved barrel domain protein.
     
 0.487
Swit_1779
PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein.
  
  
 0.485
Swit_1783
Hypothetical protein.
       0.474
Swit_1781
PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR.
       0.458
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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