Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Swit_1789TIGRFAM: putative transcriptional regulator, Rrf2 family; PFAM: protein of unknown function UPF0074. (147 aa)    
Predicted Functional Partners:
Swit_1434
Nitric oxide dioxygenase; PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; MOSC domain containing protein; Oxidoreductase FAD-binding domain protein.
 
  
 0.770
Swit_2919
TIGRFAM: putative transcriptional regulator, Rrf2 family; FeS assembly SUF system regulator, Rtf2 type; PFAM: protein of unknown function UPF0074.
  
   
 0.716
Swit_4614
Nitric oxide reductase large subunit-like protein.
     
 0.673
Swit_3173
PFAM: globin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; Belongs to the globin family.
 
   
 0.620
Swit_0051
Cysteine desulfurase; PFAM: aminotransferase, class V.
  
  
 0.565
Swit_0052
PFAM: aminotransferase, class V.
  
  
 0.565
Swit_1791
Hypothetical protein.
  
  
 0.540
Swit_1790
PFAM: multicopper oxidase, type 1; multicopper oxidase, type 2; multicopper oxidase, type 3.
     
 0.531
Swit_1709
Assimilatory nitrate reductase (NADH) alpha subunit apoprotein; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; BFD domain protein [2Fe-2S]-binding domain protein; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
  
  
 0.515
Swit_1707
TIGRFAM: nitrite reductase [NAD(P)H], large subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; nitrite/sulfite reductase, hemoprotein beta-component, ferrodoxin domain protein; nitrite and sulphite reductase 4Fe-4S region; BFD domain protein [2Fe-2S]-binding domain protein.
     
 0.506
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
Server load: low (10%) [HD]