Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Swit_1817PFAM: Erythromycin esterase. (440 aa)    
Predicted Functional Partners:
Swit_1818
PFAM: beta-lactamase.
 
  
 0.882
Swit_1820
Dihydroorotase; PFAM: amidohydrolase; D-aminoacylase domain protein; Amidohydrolase 3.
 
     0.742
Swit_1821
TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor, plug.
 
     0.726
Swit_1305
PFAM: polysaccharide biosynthesis protein.
  
     0.654
Swit_1822
Transcriptional regulator, RpiR family; PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS).
 
     0.618
Swit_1188
PFAM: monooxygenase, FAD-binding.
 
    0.602
Swit_1819
PFAM: protein of unknown function DUF1611.
       0.588
Swit_4783
Hypothetical protein.
  
  
 0.562
Swit_1186
PFAM: chalcone and stilbene synthase domain protein.
 
     0.560
Swit_1816
PFAM: protein of unknown function DUF306, Meta and HslJ.
       0.560
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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