Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Swit_1872PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding. (319 aa)    
Predicted Functional Partners:
Swit_1871
Kinase-like protein.
  
  
 0.805
Swit_1873
SMART: helix-turn-helix- domain containing protein, AraC type.
       0.675
Swit_1870
PFAM: regulatory protein, AsnC/Lrp family.
       0.640
Swit_1876
PFAM: isochorismatase hydrolase.
  
  
 0.543
Swit_1877
PFAM: short-chain dehydrogenase/reductase SDR; KR.
   
 
 0.507
Swit_1878
PFAM: FAD dependent oxidoreductase.
     
 0.485
Swit_0539
PFAM: phosphoglucomutase/phosphomannomutase C terminal; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III.
 
 
 0.472
Swit_1874
Rieske (2Fe-2S) domain protein; PFAM: ring hydroxylating dioxygenase, alpha subunit; Rieske [2Fe-2S] domain protein.
       0.471
Swit_1875
PFAM: aromatic-ring-hydroxylating dioxygenase, beta subunit.
       0.471
Swit_1869
Hypothetical protein.
  
  
 0.457
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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