Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Swit_1876PFAM: isochorismatase hydrolase. (194 aa)    
Predicted Functional Partners:
Swit_1878
PFAM: FAD dependent oxidoreductase.
 
    0.825
Swit_1877
PFAM: short-chain dehydrogenase/reductase SDR; KR.
  
 
 0.804
Swit_1874
Rieske (2Fe-2S) domain protein; PFAM: ring hydroxylating dioxygenase, alpha subunit; Rieske [2Fe-2S] domain protein.
       0.773
Swit_1875
PFAM: aromatic-ring-hydroxylating dioxygenase, beta subunit.
       0.773
Swit_1766
PFAM: isochorismatase hydrolase.
  
     0.764
Swit_2026
PFAM: isochorismatase hydrolase.
  
     0.760
Swit_4275
PFAM: isochorismatase hydrolase.
  
     0.760
Swit_0906
PFAM: isochorismatase hydrolase.
  
     0.757
Swit_1873
SMART: helix-turn-helix- domain containing protein, AraC type.
 
   
 0.625
Swit_1872
PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding.
  
  
 0.543
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.