Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
uxaCPFAM: Glucuronate isomerase. (466 aa)    
Predicted Functional Partners:
Swit_1886
PFAM: Mannitol dehydrogenase, C-terminal domain; Mannitol dehydrogenase rossman, N-terminal domain.
 
 
 0.999
Swit_1888
Transcriptional regulator, GntR family; PFAM: regulatory protein GntR, HTH; GntR domain protein.
 
   
 0.857
Swit_1693
Mandelate racemase/muconate lactonizing enzyme, N-terminal domain protein; Catalyzes the dehydration of D-mannonate. Has no detectable activity with a panel of 70 other acid sugars (in vitro).
 
   
 0.855
Swit_1890
2-keto-3-deoxygluconate kinase; PFAM: PfkB domain protein.
 
   
 0.831
Swit_1889
PFAM: Mandelate racemase/muconate lactonizing enzyme, N-terminal domain protein; Mandelate racemase/muconate lactonizing enzyme, C-terminal domain protein.
 
   
 0.828
Swit_4534
PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase, dimerisation; UDP-glucose/GDP-mannose dehydrogenase-like.
    
 0.807
Swit_1699
PFAM: PfkB domain protein.
 
   
 0.717
Swit_0742
2-keto-4-pentenoate hydratase-like protein.
 
     0.681
Swit_1883
TIGRFAM: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; PFAM: KDPG and KHG aldolase.
 
   
 0.663
Swit_1891
Transcriptional regulator, GntR family; PFAM: regulatory protein GntR, HTH; GntR domain protein.
 
   
 0.626
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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