Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Swit_1945Transcriptional regulator, Crp/Fnr family; PFAM: cyclic nucleotide-binding; regulatory protein, Crp. (242 aa)    
Predicted Functional Partners:
Swit_1477
Putative adenylate/guanylate cyclase; TIGRFAM: PAS sensor protein; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; GAF domain protein; histidine kinase, HAMP region domain protein; PAS fold-4 domain protein; PAS fold domain protein.
  
 0.666
Swit_0266
PFAM: UspA domain protein.
 
  
 0.632
Swit_1944
Transcriptional regulator, TetR family; PFAM: regulatory protein, TetR.
  
  
 0.605
Swit_1947
Hypothetical protein.
  
  
 0.567
Swit_1946
Hypothetical protein.
       0.550
Swit_4116
Putative transcriptional regulator, Crp/Fnr family; PFAM: cyclic nucleotide-binding; regulatory protein, Crp.
  
   
 0.539
Swit_2540
PFAM: response regulator receiver.
  
 
 0.537
aqpZ
MIP family channel protein; Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity; Belongs to the MIP/aquaporin (TC 1.A.8) family.
   
 0.530
Swit_2242
PFAM: major intrinsic protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.
   
 0.530
Swit_4219
PFAM: major intrinsic protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.
   
 0.530
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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