Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Swit_2050PFAM: aminoglycoside phosphotransferase. (450 aa)    
Predicted Functional Partners:
Swit_2049
Hypothetical protein.
       0.773
Swit_1479
PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain.
 
 
 0.591
Swit_3635
PFAM: MaoC domain protein dehydratase.
 
 
 0.590
Swit_4202
PFAM: Alcohol dehydrogenase, zinc-binding domain protein.
 
    0.577
Swit_0152
PFAM: Alcohol dehydrogenase, zinc-binding domain protein.
 
    0.544
Swit_2237
PFAM: AMP-dependent synthetase and ligase.
 
 
 0.526
Swit_1832
PFAM: MaoC domain protein dehydratase.
 
 
 0.525
Swit_4136
PFAM: AMP-dependent synthetase and ligase.
 
 
 0.523
Swit_0767
PFAM: AMP-dependent synthetase and ligase.
 
 
 0.510
Swit_0296
Palmitoyl-CoA hydrolase; PFAM: acyl-CoA thioesterase.
 
  
 0.479
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
Server load: low (20%) [HD]