Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Swit_2069PFAM: amidohydrolase 2. (395 aa)    
Predicted Functional Partners:
Swit_2070
PFAM: AMP-dependent synthetase and ligase.
 
   
 0.853
Swit_1742
Hypothetical protein.
  
     0.755
Swit_1965
PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein.
  
     0.735
Swit_1015
Hypothetical protein.
  
     0.720
Swit_4387
Hypothetical protein.
 
     0.716
Swit_1969
PFAM: amidohydrolase 2.
  
     0.715
Swit_3408
Hypothetical protein.
  
     0.648
Swit_3624
PFAM: protein of unknown function DUF35.
 
     0.585
Swit_0339
Hypothetical protein.
 
     0.575
Swit_3285
Hypothetical protein.
  
     0.574
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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