Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Swit_2070PFAM: AMP-dependent synthetase and ligase. (486 aa)    
Predicted Functional Partners:
Swit_2069
PFAM: amidohydrolase 2.
 
   
 0.853
Swit_2949
PFAM: AMP-dependent synthetase and ligase.
 
 
 0.837
Swit_1530
PFAM: AMP-dependent synthetase and ligase.
  
  
 
0.717
Swit_0282
PFAM: AMP-dependent synthetase and ligase.
  
  
 
0.715
Swit_3792
PFAM: AMP-dependent synthetase and ligase.
  
  
 
0.711
Swit_2067
PFAM: Enoyl-CoA hydratase/isomerase.
  
 
 0.627
Swit_2068
PFAM: Enoyl-CoA hydratase/isomerase.
  
 
 0.625
Swit_2066
PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain.
 
  
 0.524
rplF
LSU ribosomal protein L6P; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
   
 0.519
Swit_0038
PFAM: phosphoesterase, PA-phosphatase related.
    
 0.482
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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