Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Swit_2089PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein. (372 aa)    
Predicted Functional Partners:
Swit_1177
S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde.
 0.994
Swit_0382
PFAM: aldehyde dehydrogenase.
  
 0.924
Swit_0703
PFAM: aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 0.924
Swit_1000
PFAM: aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 0.924
Swit_1545
PFAM: aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 0.924
Swit_1618
PFAM: aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 0.924
Swit_1979
PFAM: aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 0.924
Swit_4298
PFAM: aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 0.924
Swit_1179
TIGRFAM: Alcohol dehydrogenase class III/S-(hydroxymethyl)glutathione dehydrogenase; PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
  
  
 
0.915
Swit_1980
PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein.
  
  
 
0.911
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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