Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Swit_2102PFAM: cyclase family protein. (309 aa)    
Predicted Functional Partners:
Swit_2099
PFAM: beta-lactamase.
 
     0.817
Swit_2101
PFAM: protein of unknown function DUF35.
 
     0.814
Swit_2103
Acetyl-CoA acetyltransferase-like protein.
 
     0.813
Swit_2100
PFAM: AMP-dependent synthetase and ligase.
     
 0.784
Swit_2098
PFAM: luciferase family protein.
 
     0.763
Swit_2096
PFAM: short-chain dehydrogenase/reductase SDR; KR.
  
  
 0.755
Swit_2097
Hypothetical protein.
       0.733
kynU
Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively.
 
  
 0.719
Swit_2108
PFAM: luciferase family protein.
 
     0.527
Swit_2104
PFAM: luciferase family protein.
 
     0.523
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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