Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Swit_2148Hypothetical protein. (236 aa)    
Predicted Functional Partners:
Swit_2147
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein.
       0.870
Swit_2146
Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein.
       0.830
Swit_2149
PFAM: protein of unknown function DUF214.
     
 0.816
Swit_2150
PFAM: ABC transporter related; SMART: AAA ATPase.
     
 0.595
Swit_2151
TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
       0.584
Swit_2152
TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: outer membrane efflux protein.
       0.584
Swit_2145
PFAM: dehydrogenase, E1 component.
       0.436
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
Server load: low (24%) [HD]