Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Swit_2159PFAM: protein of unknown function DUF1428. (117 aa)    
Predicted Functional Partners:
Swit_2158
PFAM: glutathione-dependent formaldehyde-activating, GFA.
 
    0.836
Swit_2157
PFAM: protein of unknown function DUF72.
 
     0.808
Swit_4586
PFAM: 3-demethylubiquinone-9 3-methyltransferase.
 
     0.632
Swit_2160
Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; Belongs to the LysR transcriptional regulatory family.
       0.579
Swit_2433
PFAM: AsmA family protein.
   
    0.573
Swit_2883
PFAM: Glutathione S-transferase, N-terminal domain; Glutathione S-transferase, C-terminal domain; Belongs to the GST superfamily.
 
     0.569
Swit_1108
PFAM: Activator of Hsp90 ATPase 1 family protein.
 
     0.546
Swit_2331
Hydrogenobyrinic acid a,c-diamide cobaltochelatase; TIGRFAM: cobalt chelatase, pCobS small subunit; PFAM: ATPase associated with various cellular activities, AAA_5.
       0.475
Swit_4587
PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase.
       0.475
Swit_2161
PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain.
     
 0.436
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.