Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
Swit_2242PFAM: major intrinsic protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (222 aa)    
Predicted Functional Partners:
Swit_2243
TIGRFAM: arsenate reductase; PFAM: arsenate reductase and related.
     
 0.875
Swit_2244
Transcriptional regulator, ArsR family; PFAM: regulatory protein, ArsR.
     
 0.809
Swit_2241
TIGRFAM: Arsenate resistance ArsH; PFAM: NADPH-dependent FMN reductase.
     
 0.798
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
  
 
 0.793
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
  
 
 0.743
Swit_3839
Hypothetical protein.
   
 
 0.706
Swit_4713
PFAM: glycerophosphoryl diester phosphodiesterase.
  
 
 0.700
Swit_0885
Pyroglutamyl-peptidase I; Removes 5-oxoproline from various penultimate amino acid residues except L-proline.
   
 
 0.694
Swit_0794
PFAM: Tetratricopeptide TPR_4.
    
 
 0.693
Swit_4221
PFAM: FAD dependent oxidoreductase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
  
  
 0.674
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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