Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Swit_2272PFAM: short-chain dehydrogenase/reductase SDR. (253 aa)    
Predicted Functional Partners:
Swit_2271
PFAM: Rieske [2Fe-2S] domain protein.
 
     0.801
Swit_2268
PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein.
 
 
 
 0.781
Swit_0378
PFAM: short-chain dehydrogenase/reductase SDR; KR; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
 
 
 0.778
Swit_2270
Pyruvate dehydrogenase (acetyl-transferring); PFAM: dehydrogenase, E1 component.
   
 
 0.777
Swit_2269
PFAM: Transketolase, central region; Transketolase domain protein.
  
 
 0.761
Swit_0769
PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR.
  
     0.731
Swit_3355
PFAM: short-chain dehydrogenase/reductase SDR; KR.
  
     0.724
Swit_1661
PFAM: short-chain dehydrogenase/reductase SDR; KR.
  
     0.697
Swit_1030
PFAM: short-chain dehydrogenase/reductase SDR; KR; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
     0.684
Swit_0331
PFAM: short-chain dehydrogenase/reductase SDR; KR; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
     0.682
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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