Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Swit_2273Transcriptional regulator, TetR family; PFAM: regulatory protein, TetR. (236 aa)    
Predicted Functional Partners:
Swit_2029
Hypothetical protein.
  
     0.641
Swit_2018
Hypothetical protein.
  
   
 0.609
Swit_1053
Transcriptional regulator, TetR family; PFAM: regulatory protein, TetR.
  
     0.595
Swit_2272
PFAM: short-chain dehydrogenase/reductase SDR.
 
     0.595
Swit_2271
PFAM: Rieske [2Fe-2S] domain protein.
 
     0.547
Swit_2344
Hypothetical protein.
  
     0.543
Swit_2270
Pyruvate dehydrogenase (acetyl-transferring); PFAM: dehydrogenase, E1 component.
 
     0.533
Swit_2268
PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein.
 
   
 0.525
Swit_1994
Hypothetical protein.
  
   
 0.520
Swit_2012
PFAM: FAD dependent oxidoreductase.
 
   
 0.481
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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