Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Swit_2298PFAM: monooxygenase, FAD-binding. (580 aa)    
Predicted Functional Partners:
Swit_0977
TIGRFAM: catechol 1,2-dioxygenase; PFAM: intradiol ring-cleavage dioxygenase; Catechol dioxygenase, N-terminal domain protein.
 
  
 0.928
Swit_1538
PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase.
 
  
 0.918
Swit_3045
PFAM: monooxygenase, FAD-binding; FAD dependent oxidoreductase.
  
  
 
0.913
Swit_2299
PFAM: beta-lactamase domain protein.
       0.727
Swit_2300
PFAM: TonB-dependent receptor; TonB-dependent receptor, plug.
       0.718
Swit_1438
PFAM: monooxygenase, FAD-binding; FAD dependent oxidoreductase.
  
   
 0.640
Swit_2292
PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase.
 
   
 0.609
Swit_2284
PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase.
 
   
 0.608
Swit_2449
TIGRFAM: rpsU-divergently transcribed protein; PFAM: COQ9 domain protein.
   
 0.564
Swit_1187
PFAM: Methyltransferase type 12.
  
 0.559
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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