Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Swit_2367TIGRFAM: eight transmembrane protein EpsH. (331 aa)    
Predicted Functional Partners:
atpE
H+-transporting two-sector ATPase, C subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
  
 0.993
Swit_2368
TIGRFAM: Methanolan biosynthesis EpsI.
 
     0.968
Swit_4035
SMART: AAA ATPase.
 
  
 0.794
Swit_4037
Hypothetical protein.
 
     0.780
Swit_4031
PFAM: polysaccharide export protein.
 
   
 0.777
Swit_2407
PFAM: lipopolysaccharide biosynthesis protein.
 
     0.776
Swit_4032
TIGRFAM: PEP-CTERM locus polysaccharide chain length determinant; PFAM: lipopolysaccharide biosynthesis protein.
 
     0.773
Swit_4038
PFAM: glycosyl transferase, group 1.
 
   
 0.769
Swit_4036
TIGRFAM: PEP-CTERM locus, polysaccharide deactylase; PFAM: polysaccharide deacetylase.
 
     0.758
Swit_2167
Hypothetical protein.
 
 
   0.744
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
Server load: low (14%) [HD]