STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Swit_2402Transcriptional regulator, ArsR family; PFAM: regulatory protein, ArsR; Methyltransferase type 11; Methyltransferase type 12. (323 aa)    
Predicted Functional Partners:
Swit_2401
TIGRFAM: 5,10-methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
 
   
 0.901
Swit_2400
Methionine synthase (B12-dependent); PFAM: homocysteine S-methyltransferase.
     
 0.868
Swit_2399
Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
     
 0.812
Swit_0188
PFAM: ROSMUCR transcriptional regulator.
  
   
 0.639
Swit_2403
PFAM: VacJ family lipoprotein.
       0.639
Swit_2384
PFAM: ROSMUCR transcriptional regulator.
  
   
 0.617
Swit_1802
PFAM: ROSMUCR transcriptional regulator.
  
   
 0.599
Swit_2398
Hypothetical protein.
  
  
 0.590
Swit_0590
PFAM: cyclic nucleotide-binding; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; 4Fe-4S ferredoxin, iron-sulfur binding domain protein.
  
  
 0.555
Swit_3437
PFAM: aldo/keto reductase.
  
    0.547
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.