Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Swit_2403PFAM: VacJ family lipoprotein. (315 aa)    
Predicted Functional Partners:
Swit_0442
PFAM: toluene tolerance family protein.
 
 
 
 0.886
Swit_2554
PFAM: Mammalian cell entry related domain protein.
 
   
 0.851
Swit_0689
Hypothetical protein.
   
 
 0.820
Swit_2400
Methionine synthase (B12-dependent); PFAM: homocysteine S-methyltransferase.
       0.604
Swit_2401
TIGRFAM: 5,10-methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
       0.604
Swit_2402
Transcriptional regulator, ArsR family; PFAM: regulatory protein, ArsR; Methyltransferase type 11; Methyltransferase type 12.
       0.604
Swit_2399
Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
       0.540
Swit_0481
TIGRFAM: lytic murein transglycosylase.
 
    0.526
Swit_0014
PFAM: protein of unknown function DUF140.
 
   
 0.505
Swit_0495
Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain.
 
   
 0.503
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.