Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Swit_2448PFAM: protein of unknown function DUF6, transmembrane. (311 aa)    
Predicted Functional Partners:
Swit_2449
TIGRFAM: rpsU-divergently transcribed protein; PFAM: COQ9 domain protein.
       0.870
Swit_2450
PFAM: FeoA family protein.
       0.776
Swit_2451
TIGRFAM: ferrous iron transport protein B; PFAM: GTP-binding protein, HSR1-related; Ferrous iron transport protein B domain protein; Ferrous iron transport B domain protein; nucleoside recognition domain protein.
     
 0.775
Swit_2447
PFAM: NADH:flavin oxidoreductase/NADH oxidase.
       0.755
Swit_2452
TIGRFAM: single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n.
  
    0.674
Swit_0857
Transcriptional regulator, MarR family; PFAM: regulatory protein, MarR.
 
   
 0.418
Swit_1228
Putative signal transduction protein with EFhand domain.
  
     0.408
secY
Protein translocase subunit secY/sec61 alpha; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
   
 
 0.405
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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