Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
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[Homology]
Score
Swit_2486PFAM: phosphoribosyltransferase. (170 aa)    
Predicted Functional Partners:
Swit_2485
Adenosine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.
 
 
 0.891
Swit_2484
PFAM: Bile acid:sodium symporter.
   
   0.592
Swit_2875
PFAM: GtrA family protein.
  
     0.491
Swit_0472
Hypothetical protein.
 
     0.487
Swit_3662
Hypothetical protein.
  
     0.456
Swit_3799
Hypothetical protein.
  
     0.442
Swit_1111
Hypothetical protein.
  
     0.439
Swit_2741
TIGRFAM: HAD-superfamily subfamily IB hydrolase, TIGR01490.
 
   0.438
Swit_1934
Hypothetical protein.
  
     0.426
Swit_2483
PFAM: alpha/beta hydrolase fold.
       0.424
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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