Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Swit_2492PFAM: AMP-dependent synthetase and ligase. (504 aa)    
Predicted Functional Partners:
Swit_0382
PFAM: aldehyde dehydrogenase.
  
 0.920
Swit_1000
PFAM: aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 0.920
Swit_1545
PFAM: aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 0.920
Swit_1618
PFAM: aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 0.920
Swit_1979
PFAM: aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 0.920
Swit_4298
PFAM: aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 0.920
Swit_2891
TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase; cobalamin B12-binding domain protein.
    
 0.907
Swit_0306
Hypothetical protein.
     
 0.902
Swit_2892
methylmalonyl-CoA epimerase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase.
     
 0.901
Swit_3595
PFAM: major facilitator superfamily MFS_1.
    
 0.869
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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