Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Swit_2497PFAM: Nucleotidyl transferase. (280 aa)    
Predicted Functional Partners:
Swit_2493
PFAM: polysaccharide biosynthesis protein.
 
    0.858
Swit_2496
PFAM: phosphoribosylglycinamide synthetase.
 
     0.854
ispDF
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF); In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
  
  
 0.807
Swit_3902
Hypothetical protein.
 
    0.795
Swit_4739
Hypothetical protein.
 
  
 0.785
Swit_4514
Hypothetical protein.
 
  
 0.783
Swit_3903
PFAM: diacylglycerol kinase, catalytic region.
 
     0.776
Swit_1805
Hypothetical protein.
 
  
 0.774
Swit_3908
Hypothetical protein.
 
  
 0.759
Swit_1307
Hypothetical protein; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
 
   
 0.758
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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