Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Swit_2567PFAM: amino acid permease-associated region. (507 aa)    
Predicted Functional Partners:
Swit_2566
PFAM: histidine triad (HIT) protein.
     
 0.726
hisE
PFAM: phosphoribosyl-ATP pyrophosphohydrolase.
       0.678
Swit_4613
TIGRFAM: amino acid/peptide transporter; PFAM: TGF-beta receptor, type I/II extracellular region; major facilitator superfamily MFS_1.
 
 
 
 0.488
hisF
Imidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
     
 0.487
Swit_0078
TIGRFAM: amino acid/peptide transporter; PFAM: TGF-beta receptor, type I/II extracellular region.
 
 
 
 0.486
Swit_4065
PFAM: peptidase C1A, papain.
  
 
 0.457
Swit_3733
Redoxin domain protein; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein.
  
 0.442
Swit_2821
PFAM: Ankyrin.
  
 0.431
Swit_3098
PFAM: Ankyrin.
  
 0.431
Swit_2629
PFAM: sodium:dicarboxylate symporter; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
 
 
 0.406
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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