Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Swit_2572Transcriptional regulator, HxlR family; PFAM: helix-turn-helix, HxlR type. (169 aa)    
Predicted Functional Partners:
Swit_2573
PFAM: 2OG-Fe(II) oxygenase; SMART: Prolyl 4-hydroxylase, alpha subunit.
       0.690
Swit_2281
Transcriptional regulator, HxlR family; PFAM: helix-turn-helix, HxlR type.
  
     0.683
Swit_2571
PFAM: bifunctional deaminase-reductase domain protein.
 
     0.666
Swit_2570
PFAM: Glutathione S-transferase, N-terminal domain.
       0.624
Swit_4602
PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase.
 
    0.459
Swit_2574
Hypothetical protein.
       0.446
Swit_3386
Transcriptional modulator of MazE/toxin, MazF; PFAM: PemK family protein.
   
    0.430
Swit_4881
Transcriptional modulator of MazE/toxin, MazF.
   
    0.430
Swit_4585
PFAM: GCN5-related N-acetyltransferase.
 
     0.401
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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