nadE protein (Sphingomonas wittichii) - STRING interaction network

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nadE

NAD(+) synthase (glutamine-hydrolyzing); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (687 aa)

Predicted Functional Partners:

nadD

0.957

cobB

0.949

nadK

0.949

Swit_1181

0.936

Swit_4689

0.925

Swit_1182

0.907

Swit_1183

0.907

Swit_0253

0.903

Swit_2592

0.733

Swit_2593

0.733

Your Current Organism:

Sphingomonas wittichii

NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Swit_0253	Swit_1181	Swit_0253	Swit_1181	TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase.	NAD(P)(+) transhydrogenase (AB-specific); The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.	0.903
Swit_0253	Swit_1182	Swit_0253	Swit_1182	TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase.	NAD/NADP transhydrogenase alpha subunit-like protein.	0.903
Swit_0253	Swit_1183	Swit_0253	Swit_1183	TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase.	PFAM: alanine dehydrogenase/PNT domain protein.	0.903
Swit_0253	Swit_4689	Swit_0253	Swit_4689	TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase.	PFAM: NUDIX hydrolase; NADH pyrophosphatase-like-like; Zinc ribbon, NADH pyrophosphatase.	0.909
Swit_0253	cobB	Swit_0253	Swit_0207	TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase.	PFAM: Silent information regulator protein Sir2; Belongs to the sirtuin family. Class III subfamily.	0.903
Swit_0253	nadD	Swit_0253	Swit_2543	TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase.	Cytidylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).	0.907
Swit_0253	nadE	Swit_0253	Swit_2595	TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase.	NAD(+) synthase (glutamine-hydrolyzing); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.	0.903
Swit_0253	nadK	Swit_0253	Swit_1521	TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase.	NAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.	0.903
Swit_1181	Swit_0253	Swit_1181	Swit_0253	NAD(P)(+) transhydrogenase (AB-specific); The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.	TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase.	0.903
Swit_1181	Swit_1182	Swit_1181	Swit_1182	NAD(P)(+) transhydrogenase (AB-specific); The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.	NAD/NADP transhydrogenase alpha subunit-like protein.	0.999
Swit_1181	Swit_1183	Swit_1181	Swit_1183	NAD(P)(+) transhydrogenase (AB-specific); The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.	PFAM: alanine dehydrogenase/PNT domain protein.	0.999
Swit_1181	Swit_4689	Swit_1181	Swit_4689	NAD(P)(+) transhydrogenase (AB-specific); The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.	PFAM: NUDIX hydrolase; NADH pyrophosphatase-like-like; Zinc ribbon, NADH pyrophosphatase.	0.900
Swit_1181	cobB	Swit_1181	Swit_0207	NAD(P)(+) transhydrogenase (AB-specific); The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.	PFAM: Silent information regulator protein Sir2; Belongs to the sirtuin family. Class III subfamily.	0.903
Swit_1181	nadD	Swit_1181	Swit_2543	NAD(P)(+) transhydrogenase (AB-specific); The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.	Cytidylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).	0.907
Swit_1181	nadE	Swit_1181	Swit_2595	NAD(P)(+) transhydrogenase (AB-specific); The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.	NAD(+) synthase (glutamine-hydrolyzing); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.	0.936
Swit_1181	nadK	Swit_1181	Swit_1521	NAD(P)(+) transhydrogenase (AB-specific); The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.	NAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.	0.909
Swit_1182	Swit_0253	Swit_1182	Swit_0253	NAD/NADP transhydrogenase alpha subunit-like protein.	TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase.	0.903
Swit_1182	Swit_1181	Swit_1182	Swit_1181	NAD/NADP transhydrogenase alpha subunit-like protein.	NAD(P)(+) transhydrogenase (AB-specific); The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.	0.999
Swit_1182	Swit_1183	Swit_1182	Swit_1183	NAD/NADP transhydrogenase alpha subunit-like protein.	PFAM: alanine dehydrogenase/PNT domain protein.	0.999
Swit_1182	Swit_4689	Swit_1182	Swit_4689	NAD/NADP transhydrogenase alpha subunit-like protein.	PFAM: NUDIX hydrolase; NADH pyrophosphatase-like-like; Zinc ribbon, NADH pyrophosphatase.	0.900

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