Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Swit_2636PFAM: short-chain dehydrogenase/reductase SDR; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (260 aa)    
Predicted Functional Partners:
Swit_2634
PFAM: ring hydroxylating dioxygenase, alpha subunit; Rieske [2Fe-2S] domain protein.
 
 
 0.994
Swit_2635
2-chlorobenzoate 1,2-dioxygenase; PFAM: aromatic-ring-hydroxylating dioxygenase, beta subunit.
 
 
 0.994
Swit_0977
TIGRFAM: catechol 1,2-dioxygenase; PFAM: intradiol ring-cleavage dioxygenase; Catechol dioxygenase, N-terminal domain protein.
 
  
 0.975
Swit_1538
PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase.
   
 
 0.903
Swit_2633
Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; Belongs to the LysR transcriptional regulatory family.
 
     0.807
Swit_0976
PFAM: Muconolactone delta-isomerase.
 
   
 0.782
Swit_1757
PFAM: aromatic-ring-hydroxylating dioxygenase, beta subunit.
 
  
 0.774
Swit_1875
PFAM: aromatic-ring-hydroxylating dioxygenase, beta subunit.
 
  
 0.760
Swit_0975
TIGRFAM: muconate and chloromuconate cycloisomerase; PFAM: Mandelate racemase/muconate lactonizing enzyme, N-terminal domain protein; Mandelate racemase/muconate lactonizing enzyme, C-terminal domain protein.
 
   
 0.740
Swit_1532
PFAM: aromatic-ring-hydroxylating dioxygenase, beta subunit.
 
  
 0.727
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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