Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Swit_2680TIGRFAM: Double-strand break repair protein AddB. (991 aa)    
Predicted Functional Partners:
Swit_2681
TIGRFAM: Double-strand break repair helicase AddA; PFAM: UvrD/REP helicase; Belongs to the helicase family. UvrD subfamily.
 
   
 0.980
Swit_2682
TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; Belongs to the thioredoxin family.
  
    0.792
Swit_2541
Outer membrane lipoprotein carrier protein LolA; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
 
     0.763
Swit_2332
PFAM: heat shock protein DnaJ domain protein.
 
     0.759
Swit_2716
PFAM: protein of unknown function DUF1321.
  
     0.746
Swit_2850
TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III, delta.
 
   
 0.741
Swit_4471
PFAM: Protein of unknown function DUF1790.
  
     0.732
lptD
Organic solvent tolerance protein; Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane; Belongs to the LptD family.
  
     0.724
Swit_4584
PFAM: protein of unknown function DUF1058.
  
     0.720
recO
DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination.
 
   
 0.713
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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