Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Swit_2722NADPH-glutathione reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region. (448 aa)    
Predicted Functional Partners:
Swit_0017
PFAM: Glutathione S-transferase, N-terminal domain; Glutathione S-transferase, C-terminal domain.
 
 0.948
gshB
TIGRFAM: glutathione synthetase; PFAM: glutathione synthetase domain protein; glutathione synthetase, ATP-binding; RimK domain protein ATP-grasp; Belongs to the prokaryotic GSH synthase family.
 
  
 0.948
Swit_4077
PFAM: glutathione peroxidase; Belongs to the glutathione peroxidase family.
  
 0.948
Swit_1225
Transketolase, central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
  
 0.947
Swit_3667
PFAM: Thioredoxin domain.
  
 
 0.945
Swit_4722
PFAM: Glutathione S-transferase, N-terminal domain.
  
 0.940
Swit_1199
PFAM: glutathione peroxidase; Belongs to the glutathione peroxidase family.
  
 0.930
Swit_2570
PFAM: Glutathione S-transferase, N-terminal domain.
  
 0.927
Swit_1646
PFAM: Glutathione S-transferase, N-terminal domain.
  
 0.925
Swit_4120
PFAM: Glutathione S-transferase, N-terminal domain; Glutathione S-transferase, C-terminal domain; Belongs to the GST superfamily.
  
 0.925
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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