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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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textmining
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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Score
Swit_2732Aconitase; PFAM: aconitate hydratase domain protein; aconitate hydratase 2. (921 aa)    
Predicted Functional Partners:
Swit_0457
TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: isocitrate/isopropylmalate dehydrogenase; Belongs to the isocitrate and isopropylmalate dehydrogenases family.
  
 
 0.982
Swit_3212
TIGRFAM: citrate synthase I; PFAM: Citrate synthase; Belongs to the citrate synthase family.
  
 
 0.952
Swit_4790
TIGRFAM: 2-methylcitrate synthase/citrate synthase II; PFAM: Citrate synthase; Belongs to the citrate synthase family.
  
 
 0.952
Swit_2926
PFAM: isocitrate lyase and phosphorylmutase.
  
 
 0.922
Swit_4791
2,3-dimethylmalate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.
  
 
 0.922
Swit_2731
Aconitase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
    
 0.920
mdh
Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
  
  
 0.919
Swit_4788
Methylitaconate delta2-delta3-isomerase; TIGRFAM: putative AcnD-accessory protein PrpF; PFAM: protein of unknown function DUF453.
    
 0.913
Swit_1298
TIGRFAM: 2-oxoglutarate dehydrogenase, E1 subunit; PFAM: dehydrogenase, E1 component; Transketolase, central region.
  
  
 0.892
Swit_4672
Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
  
 0.871
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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